Friday, June 26, 2009

What is your favorite bug? For me nothing beats Pseudomonas aeruginosa

What is everybody's favorite bug? Mine is Pseudomonas aeruginosa, who doesn't love the pseudo smell in the morning? One of the main reasons it is my favorite is that it is such a versatile organism that thrives in many locations. Also, fact that it secretes a wide variety of pigments like Pyocyanin. Pyocyanin is a redox-active virulence factor produced by Pseudomonas aeruginosa that allows it to kill cells, disrupts cilia actions, inhibit lymphocyte proliferation, and alter phagocytic function. (P.aeruginosa can also preoduce fluorescein, and pyorubin.) The following pic shows growth on BHI with a pyocyanin producing P.aeruginosa on the left and a negative control on the right.One of the other coolest features about P.aeruginosa is that it is capable of growing in diesel fuel and jet fuel, which is known as a hydrocarbon-utilizing microrganism. Definately has some future applications as we take a steer towards a greener society! So let everyone know what your favorite bug is!

10 comments:

GERMAN ESPARZA said...

What about Carbapenem resistance in P.areuginosa

Paul "Stork" Renick said...

My personal favorite is Staphylococcus aureus but I'm biased since it is the "bug" I've done the most work with in my career

Anonymous said...

Hello, I have cultured a bacteria (possibly MRSA) in a petri dish and I'm trying to do an initial identification before I transfer to slides and a microscope. The color of the item is bright red on a Q-tip and then going away from the center it becomes crusty brown fading out to yelloow then to white "feathery" fingers....

Anonymous said...

To Anonymous, Sounds like a mould to me. MRSA will be milky white-yellowish. Some Serratia species are bright red, but I have never seen one with the white feathery fingers. You can tell a lot by looking at it with a good microscope.

Anonymous said...

I'd recently isolated the same bacteria that you're having, first i though it was a E. coli but it produce the pyocyanin on both my NA & PDA media. It has potential in my area of studies, however, since it is potential pathogen at the same time, I'm still thinking want to cont. my work on it or not...
Besides production of pyocyanin, any test you recommend to test its identity? The one I'm having is suspected to be clinical isolate (mucoid appearance instead of small rough colony).

Anonymous said...

Hmmm.. call me crazy, but I'm a Proteus fan. Of course I do love me some aeruginosa, but to me, proteus has a "chocolatey" smell that I like. I immediately know when there is proteus on the plates before even looking at them due to the smell, which is pleasant to me. Granted, proteus is a huge pain in my rear, but I do love the smell. Providencia also smells proteus-y to me as well.

Viagra Online said...

Wow it's amazing that something alive can grown up in diesel or gasoline, no one that I know would be capaple of made it.
Nice post, thanks.

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